What is throat cancer?
Throat cancer generally refers to cancers that start in the pharynx or larynx (voice box), but can also refer to cancers that start in the oesophagus (food pipe) or thyroid. Some cancers which begin in the throat area, as well as the tongue, salivary glands, sinuses, nose or ear, are classified as head and neck cancers.
The two main types of cancer that are commonly referred to as throat cancers are pharyngeal and laryngeal cancers - cancer of the pharynx and the larynx.
Throat cancer signs and symptoms
Symptoms for throat cancers can include:
throat pain
shortness of breath
persistent sore throat or cough
coughing up blood
changes to the voice such as hoarseness
difficulties swallowing
feeling there is something stuck in the throat
lumps in the neck or throat
sudden unexplained weight loss
Causes of throat cancer
Risk factors for throat cancers include:
smoking tobacco
excessive alcohol consumption
human papillomavirus (HPV)
epstein-barr virus (EBV)
poor diet
family history of cancer
Diagnosis of throat cancer
Tests to diagnose pharyngeal or laryngeal cancer may include:
Physical examination
Your doctor will examine your mouth, throat and neck and may insert a gloved finger into your mouth to examine areas that are difficult to see.
Blood tests
Samples may be taken to check your general health.
Biopsy
The doctor will remove a small sample of tissue or cells for examination under a microscope to see if cancer cells are present.
Endoscopy of the larynx
A thin tube with a light on its end (endoscope) will be inserted through the nose to look for abnormalities in the throat.
Ultrasound
A small device called a transducer is used to send out soundwaves that echo when they hit something dense such as an organ or tumour.
X-rays
You may have a chest x-ray to check your overall health or to see if cancer has spread to the lungs.
CT scan
A CT (computerised tomography) scan uses x-ray beams to create detailed cross-sectional images of inside your body.
MRI
An MRI (magnetic resonance imaging) scan uses magnet and radio waves to create detailed images of the inside of your body.
PET scan
A PET (positron emission tomography) scan combined with a CT scan, is often recommended. Radioactive material is injected into the body to help show cancer cells.
After a diagnosis of throat cancer
After finding out you have throat cancer, you may experience a range of emotions such as disbelief, confusion and sadness and feelings of loss of control. These reactions are normal and you may find it helpful to talk to family and friends about how you feel.
Talk to your doctor about treatments that are available to you, potential side effects and how soon you should start treatment. Take as much time as you can before making a decision.
Treatment for throat cancer
Treatment will depend on the size of the cancer, whether it has spread and your overall health
Staging
Tests for throat cancers will confirm if you have cancer and how far it has spread. This is called staging and will help your doctors determine the best treatment options for you. Treatments for throat cancers include surgery, radiation therapy (radiotherapy) and chemotherapy, or a combination of one or more of these.
Surgery
Depending on the size of the tumour, you may be recommended surgery to have it removed. The type of surgery will also depend on the location of the cancer and may involve removing part of the pharynx or the partial or full removal of the larynx, thyroid or tongue.
Radiation therapy (radiotherapy)
After surgery, you may also receive radiation therapy (also known as radiation therapy). In some cases radiotherapy will be the principal treatment type.
Chemotherapy
In some instances, chemotherapy may be required along with radiation, particularly if the tumours are large or the cancer has spread to the lymph nodes. Chemotherapy may also be used to shrink tumours prior to surgery.
Treatment Team
Depending on your treatment, your treatment team may consist of a number of different health professionals, such as:- GP (General Practitioner) -
looks after your general health and works with your specialists to coordinate treatment.
- Ear, nose and throat (ENT) specialist -
treats disorders of the ear, nose and throat
- Head and neck surgeon -
diagnoses and treats cancers of the head and neck.
- Oral surgeon -
treats disorders of the mouth, face and jaws.
- Dentist -
evaluates and treats the mouth and teeth
- Radiation oncologist -
prescribes and coordinates radiation therapy treatment.
- Medical oncologist -
prescribes and coordinates the course of chemotherapy.
- Cancer nurse -
assists with treatment and provides information and support throughout your treatment.
- Dietitian -
recommends an eating plan to follow while you are in treatment and recovery.
- Pathologist -
examines cells and tissues under a microscope
- Physiotherapist/occupational therapist -
help with physical and practical problems such as restoring movement and mobility after treatment.
- Other allied health professionals -
such as social workers, pharmacists, and counsellors
Screening for throat cancer
There is currently no national screening program for throat cancers available in Australia.
Preventing throat cancer
Around 60% of pharyngeal and laryngeal cancers in Australia are caused by smoking; around 30% are caused by excess alcohol consumption. So quitting smoking and moderating alcohol consumption will significantly reduce your risk of developing throat cancer.
Prognosis for throat cancer
Your doctor will not be able to predict the exact course of the disease, as it will depend on individual circumstances such as the type of throat cancer you have and how far it has spread, your age, medical history and overall health.
Sources
- Understanding Head and Neck Cancers, Cancer Council Australia, © 2024. Last medical review of source booklet: February 2024. We thank the reviewers of this booklet: A/Prof Martin Batstone, Oral and Maxillofacial Surgeon and Director of the Maxillofacial Unit, Royal Brisbane and Women’s Hospital, QLD; Polly Baldwin, 13 11 20 Consultant, Cancer Council SA; Martin Boyle, Consumer; Dr Teresa Brown, Assistant Director Dietetics, Royal Brisbane and Women’s Hospital, Honorary Associate Professor, University of Queensland, QLD; Dr Hayley Dixon, Head, Clinical Support Dentistry Department, WSLHD Oral Health Services, Public Health Dentistry Specialist, NSW; Head and Neck Cancer Care Nursing Team, Royal Melbourne Hospital, VIC; Rhys Hughes, Senior Speech Pathologist, Peter MacCallum Cancer Centre, VIC; Dr Annette Lim, Medical Oncologist and Clinician Researcher – Head and Neck and Non-melanoma Skin Cancer, Peter MacCallum Cancer Centre, VIC; Dr Sweet Ping Ng, Radiation Oncologist, Austin Health, VIC; Deb Pickersgill, Senior Clinical Exercise Physiologist, Queensland Sports Medicine Centre, QLD; John Spurr, Consumer; Kate Woodhead, Physiotherapist, St Vincent’s Health, Melbourne, VIC; A/Prof Sue-Ching Yeoh, Oral Medicine Specialist, University of Sydney, Sydney Oral Medicine, Royal Prince Alfred Hospital, Chris O’Brien Lifehouse, NSW
- Australian Institute of Health and Welfare. ACIM (Australian Cancer Incidence and Mortality) Books. Canberra: AIHW.
- Australian Institute of Health and Welfare. Cancer data in Australia [Internet]. Canberra: Australian Institute of Health and Welfare, 2024 Available from: https://www.aihw.gov.au/reports/cancer/cancer-data-in-australia
Last updated: 14 August 2024
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