Oncogenic HPV types not detected

Women in whom oncogenic HPV types are not detected are at very low risk of cervical intraepithelial neoplasia grade 3 (CIN3) and cervical cancer for at least 5 years (see Chapter 2. The rationale for primary HPV screening).[1][2] MSAC recommended that these women can continue 5-yearly screening (see Medical Services Advisory Committee recommendations for HPV testing).[3]

Flowchart 6.2 Cervical screening pathway for primary oncogenic HPV testing (HPV not detected)

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Author(s):

• Professor Karen Canfell — Co-author
• Professor Ian Hammond — Co-author
• Professor Marion Saville — Co-author
• Cancer Council Australia Cervical Cancer Screening Guidelines Working Party — Co-author

References

1. Katki HA, Kinney WK, Fetterman B, Lorey T, Poitras NE, Cheung L, et al. Cervical cancer risk for women undergoing concurrent testing for human papillomavirus and cervical cytology: a population-based study in routine clinical practice. Lancet Oncol 2011 Jul;12(7):663-72 Available from: http://www.ncbi.nlm.nih.gov/pubmed/21684207.
2. Dillner J, Rebolj M, Birembaut P, Petry KU, Szarewski A, Munk C, et al. Long term predictive values of cytology and human papillomavirus testing in cervical cancer screening: joint European cohort study. BMJ 2008 Oct 13;337:a1754 Available from: http://www.ncbi.nlm.nih.gov/pubmed/18852164.
3. Medical Services Advisory Committee. MSAC Outcomes. Application No. 1276 – Renewal of the National Cervical Screening Program. [homepage on the internet] Canberra: Australian Government Department of Health; 2014 [updated 2015 Apr]. Available from: http://www.msac.gov.au/internet/msac/publishing.nsf/Content/FD36D6990FFAA639CA25799200058940/$File/1276%20-%20Final%20MSAC%20PSD%20-%20NCSP%20Renewal.pdf.

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